Related Experiment Videos
Protein kinase modulation of mu opioid receptor signalling
L Yu1
1Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis 46202, USA.
Cellular Signalling
|August 1, 1996
Abstract:
The mu opioid receptor mediates the pain-relieving effects of opioid narcotics. Cellular signalling of the mu receptor involves G-proteins, and the effectors include adenylyl cyclase and ion channels. Studies in which the cloned mu opioid receptor is used for cellular expression show that the receptor function is modulated by multiple protein kinases.