Related Experiment Videos
Possible paroxetine-induced bruxism
F Romanelli1, D A Adler, K M Bungay
1University of Kentucky Medical Center, Lexington 40536, USA.
The Annals of Pharmacotherapy
|November 1, 1996
Summary
This case study highlights a patient experiencing bruxism potentially caused by paroxetine, a selective serotonin reuptake inhibitor (SSRI). The bruxism symptoms significantly improved after treatment with buspirone.
Area of Science:
- Psychiatry
- Pharmacology
- Dentistry
Background:
- Selective serotonin reuptake inhibitors (SSRIs) are commonly prescribed for depression.
- Bruxism, characterized by teeth grinding and clenching, has been linked to certain SSRIs like fluoxetine and sertraline.
- The potential for paroxetine to induce bruxism requires clinical attention.
Observation:
- A 20-year-old woman developed dental damage consistent with bruxism after initiating paroxetine for depression.
- The patient's bruxism symptoms, including tooth pain and jaw tenderness, emerged after paroxetine dosage adjustments.
- Dental examinations prior to paroxetine therapy had not revealed any tooth damage.
Findings:
- The case suggests a potential link between paroxetine use and the development of bruxism.
- Treatment with buspirone resulted in a significant reduction in the patient's bruxism symptoms.
- This response to buspirone aligns with previous reports on managing SSRI-induced bruxism.
Implications:
- Clinicians should consider paroxetine as a potential cause of new-onset bruxism in patients.
- Buspirone may be an effective therapeutic option for managing paroxetine-induced bruxism.
- Further research into the mechanisms of SSRI-induced bruxism is warranted.