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[Magnesium concentration in erythrocytes and plasma in childhood (author's transl)]
Deutsche Medizinische Wochenschrift (1946)
|July 22, 1977
Insights
Magnesium levels in children
Area of Science:
- Pediatric Medicine
- Biochemistry
- Human Physiology
Context:
- Longitudinal study tracking magnesium levels from birth through school age.
- Compares infant, child, and adult magnesium concentrations.
- Includes analysis of maternal and umbilical cord blood magnesium.
Purpose:
- To determine the developmental changes in magnesium concentration in children.
- To establish reference ranges for erythrocyte and plasma magnesium in pediatric populations.
- To investigate the relationship between maternal, neonatal, and childhood magnesium levels.
Summary:
- Magnesium concentration in both plasma and erythrocytes consistently increases from birth to school age.
- Significant differences in magnesium levels were observed between newborns (1-7 days), infants (2-6 weeks), and school-aged children (6-14 years).
- Adult controls showed statistically different magnesium levels compared to both mothers postpartum and school-aged children.
Impact:
- Provides crucial data on normal magnesium development in children.
- Highlights potential implications for pediatric health and nutritional status.
- Establishes normative values for magnesium in erythrocytes and plasma across different pediatric age groups.
Abstract:
In 243 children of various ages the magnesium concentration was determined simultaneously in erythrocytes and plasma. The analysis began in the mother immediately after delivery, in the umbilical vein and in the newborn infant, and ended at school age (6-14 years). The magnesium concentration in plasma as well as in the erythrocytes showed a constant tendency to increase. Statistically significant differences occurred between the age group 1-7 days on the one hand and 2-6 weeks on the other, and also between school children and adult controls (n=20). The adult controls also differed statistically from mothers following delivery.