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Effects of nadolol and its combination with atrial pacing on rate-enhanced ventricular premature complexes
M V Pitzalis1, F Mastropasqua, F Massari
1Institute of Cardiology, University of Bari, Italy.
The American Journal of Cardiology
|November 15, 1996
Abstract:
To explore the role of heart rate in the genesis of ventricular premature complexes whose incidence increases when the length of the preceding cardiac cycle decreases, we analyzed the effect of nadolol alone and together with atrial pacing in 4 patients. Nadolol lengthened the RR cycle and suppressed ventricular premature complexes; atrial pacing, restoring the baseline RR cycle lengths, led to the reappearance of ventricular premature complexes, suggesting the major role of heart rate.