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Updated: Aug 10, 2026

Partial Heterotopic Hindlimb Transplantation Model in Rats
Published on: June 9, 2021
Lability of the presumptive pectoral and pelvic girdle territories compared using celomic grafts
D M Smith1, M R Stark, T D Stephens
1Department of Biological Sciences, Idaho State University, Pocatello 83209, USA.
Abstract:
The concept of "limbness" usually implies "wingness" or "legness". We present evidence in this study that in the case of the proximal forelimb, limbness may exist independent of wingness. Presumptive wing and leg regions were grafted into the opposite limb (wing into leg or leg into wing) of stage 18 hosts. Several stage 10+ to 11+ presumptive wing regions grafted into host legs developed pelvic girdles associated with distal wing elements. This phenomenon was not seen in presumptive wing region grafts older than stage 12-. Presumptive leg regions grafted into host wings developed leg structures only, including pelvic girdle and leg digits. The pectoral girdle appears to be labile in early stages, whereas the pelvic girdle is not labile even during early stages.

