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Anthelmintic resistant nematodes in goats in The Netherlands
F H Borgsteede1, J J Pekelder, D P Dercksen
1DLO-Institute for Animal Science and Health, Lelystad, Netherlands.
Veterinary Parasitology
|October 15, 1996
Summary
Anthelmintic resistance in goats was confirmed, with oxfendazole showing reduced efficacy against common gastrointestinal nematodes. Levamisole and ivermectin remained effective, indicating potential treatment options for resistant parasite infections.
Area of Science:
- Veterinary Parasitology
- Animal Health
- Anthelmintic Resistance
Background:
- Anthelmintic resistance poses a significant threat to livestock health and productivity.
- Goats, particularly Angora and Anglo-Nubian breeds, can harbor gastrointestinal nematodes.
- Confirmation of resistance is crucial for effective parasite management strategies.
Purpose of the Study:
- To confirm a suspected case of anthelmintic resistance in goats.
- To evaluate the efficacy of oxfendazole, ivermectin, and levamisole against goat-derived nematodes.
Main Methods:
- Sheep lambs were experimentally infected with goat-derived nematode larvae.
- Treated groups received oxfendazole, ivermectin, or levamisole.
- Post-mortem worm counts were performed to assess drug efficacy.
Main Results:
- Benzimidazole resistance was confirmed in Haemonchus contortus, Teladorsagia circumcincta, Cooperia curticei, and Trichostrongylus colubriformis.
- Oxfendazole efficacy ranged from 21% to 68% against these nematodes.
- Levamisole and ivermectin demonstrated full efficacy, with no resistance observed.
Conclusions:
- The study confirmed benzimidazole resistance in key goat nematode species.
- Oxfendazole is not recommended for treating these resistant parasite populations.
- Levamisole and ivermectin are viable alternatives for controlling these nematode infections in goats.