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Related Experiment Videos

Apoptosis -- the story so far

A Samali1, A M Gorman, T G Cotter

  • 1Department of Biochemistry, University College, Lee Maltings, Cork, Ireland.

Experientia
|October 31, 1996
PubMed
Summary

Programmed cell death, or apoptosis, is a universal cell death mechanism distinct from necrosis. This issue discusses the various components of the eukaryotic cell death machinery.

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Cell death & disease·2015

Area of Science:

  • Biological Sciences
  • Cell Biology
  • Molecular Biology

Background:

  • Programmed cell death, known as apoptosis, is a fundamental biological process.
  • Apoptosis is a widely accepted mechanism of cell death, distinct from necrosis.
  • Research into apoptosis has intensified over the last two decades.

Purpose of the Study:

  • To provide an overview of the components involved in programmed cell death.
  • To discuss the machinery of apoptosis in eukaryotic cells.
  • To consolidate current understanding of apoptosis.

Main Methods:

  • Literature review of programmed cell death.
  • Discussion of eukaryotic cell death components.
  • Synthesis of established concepts in apoptosis research.

Main Results:

  • Apoptosis is a universal and common form of cell death.
  • The distinction between apoptosis and necrosis is well-established.
  • Key components of the eukaryotic cell death machinery are identified.

Conclusions:

  • Apoptosis is a critical area of study in biological sciences.
  • Understanding apoptosis is crucial for various biological processes.
  • This issue provides insights into the complex mechanisms of cell death.

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