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Updated: Aug 7, 2026

In vivo Application of the REMOTE-control System for the Manipulation of Endogenous Gene Expression
Published on: March 29, 2019
The intron-exon structure of the porcine E-selectin-encoding gene
H Winkler1, C Brostjan, V Csizmadia
1Sandoz Center for Immunobiology, New England Deaconess Hospital, Harvard Medical School, Boston, MA 02215, USA. hwinkler@nedhmail.nedh.harvard.edu
Abstract:
We have cloned and sequenced the gene encoding porcine E-selectin. The gene comprises 12 exons and 11 introns. Two pseudoexons are contained within intron 4 and intron 6. These sequences are similar to the corresponding exons in the human E-selectin sequence; however, they are not present in the porcine E-selectin-encoding cDNA. Transcription starts at position -498 relative to the translation initiation site. The first ATG is located within exon 2. Translation stops in exon 11 leaving exon 12 untranslated in its entirety.
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