Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Low cholesterol and cancer

H Kritz1, C Zielinski, H Sinzinger

  • 1Department of Nuclear Medicine, University of Vienna, Austria.

Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology
|November 1, 1996
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

ESMO-Magnitude of Clinical Benefit Scale version 2.0 (ESMO-MCBS v2.0).

Annals of oncology : official journal of the European Society for Medical Oncology·2025
Same author

ESMO Open: from Cancer Horizons to Science for Optimal Cancer Care-a tale stretching over 8 years.

ESMO open·2023
Same author

COP27 Climate Change Conference: urgent action needed for Africa and the world.

Annals of oncology : official journal of the European Society for Medical Oncology·2022
Same author

Introducing pro and con discussions in ESMO Open-Cancer Horizons.

ESMO open·2022
Same author

ESMO Clinical Practice Guidelines: adapting and adopting new approaches for development, implementation and audit.

ESMO open·2022
Same author

Biases in study design, implementation, and data analysis that distort the appraisal of clinical benefit and ESMO-Magnitude of Clinical Benefit Scale (ESMO-MCBS) scoring.

ESMO open·2021
Same journal

Reply to: Olaparib in Metastatic Breast Cancer: The Impact of Prior Cyclin-Dependent Kinase 4 and 6 Inhibitor Exposure on Efficacy.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology·2026
Same journal

Uncontrolled Prediabetes Confounding in the Association Between Alcohol Consumption and Young-Onset Pancreatic Cancer.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology·2026
Same journal

Brain-Only Progression After First-Line Therapy in Extensive-Stage Small Cell Lung Cancer: Treat the Sanctuary, Preserve the Backbone.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology·2026
Same journal

Reply to: "Beyond Average Grams: Aldehyde Dehydrogenase 2*2  and Alcohol-Induced Young-Onset Pancreatic Cancer" and "Uncontrolled Prediabetes Confounding in the Association Between Alcohol Consumption and Young-Onset Pancreatic Cancer".

Journal of clinical oncology : official journal of the American Society of Clinical Oncology·2026
Same journal

Beyond Average Grams: Aldehyde Dehydrogenase 2*2 and Alcohol-Induced Young-Onset Pancreatic Cancer.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology·2026
Same journal

Olaparib in Metastatic Breast Cancer: The Impact of Prior Cyclin-Dependent Kinase 4 and 6 Inhibitor Exposure on Efficacy.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology·2026
See all related articles

The relationship between plasma cholesterol and mortality is complex, with potential links to both heart disease and cancer. Current evidence does not suggest that lower cholesterol causes cancer, and cholesterol-lowering drugs may aid cancer treatment.

Area of Science:

  • Cardiovascular Medicine
  • Oncology
  • Epidemiology

Background:

  • Plasma cholesterol concentration exhibits a complex relationship with mortality.
  • Elevated cholesterol is linked to increased coronary heart disease mortality.
  • Some studies suggest a negative correlation between cholesterol and cancer mortality.

Purpose of the Study:

  • To explore the intricate relationship between plasma cholesterol levels and mortality from cardiovascular disease and cancer.
  • To investigate whether the benefits of lipid reduction for heart disease could be negated by increased cancer mortality.
  • To discuss current insights into lipid metabolism and cancer.

Main Methods:

  • Comprehensive literature search of MedLine database.
  • Inclusion of studies published up to January 1996.

Related Experiment Videos

  • Systematic review of existing research on cholesterol and mortality.

    • Main Results:

    • No current evidence supports a causal link between low cholesterol and increased cancer risk.
    • The association between low cholesterol and higher cancer risk is not definitively established as causal.
    • Available data do not indicate that lower cholesterol levels cause cancer.

    Conclusions:

    • Physicians should continue advising patients on cardiovascular disease risk factors, including cholesterol management.
    • Hypercholesterolemia drugs may have potential as adjuncts in cancer therapy.
    • Cholesterol-lowering medications might offer benefits in cancer prevention and treatment.