[2-formyl-1,4-benzodioxane. Preparation and reactivity]

The preparation of 2-formyl-1.4-benzodioxane by reduction of the corresponding ethyl ester, and some reactions of this aldehyde carried out with the aim of obtaining new pharmacologically active derivatives, are described. Wittig reactions with stabilized, semi-stabilized, and reactive phosphoranes resulted in the formation of the 2-alkenyl derivatives. Reaction with a primary amine led to the corresponding imine. The 1.3-dithiane was also prepared and its behaviour with strong bases and alkylating reagents investigated.