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Updated: Aug 6, 2026

A Microfluidic Flow Chamber Model for Platelet Transfusion and Hemostasis Measures Platelet Deposition and Fibrin Formation in Real-time
Published on: February 14, 2017
Biochemical effects in women following one year's exposure to a new triphasic contraceptive--II. coagulation profiles
1Department of Obstetrics and Gynecology, Texas Tech University Health Sciences Center, Lubbock 79430, USA.
Abstract:
1. Coagulation variables were determined in 14 contraceptive nonusers and 25 prior contraceptive users at 3, 6, and 12 months' exposure to a new oral form of progestin. 2. Overall hemostasis was unaffected, as was the intrinsic pathway. 3. Changes were noted in several vitamin-K dependent factors along with a marked decrease in fibrinogen. 4. Protein C antigen (a coagulation inhibitor), was elevated. 5. This new triphasic contraceptive appears to have a minimal influence on thrombosis while activating antithrombotic protein C. The data suggest a favorable hematologic response to this contraceptive.
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