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Prisoner subjects and drug testing

L Lasagna

    Federation Proceedings
    |September 1, 1977
    PubMed
    Summary
    This summary is machine-generated.

    Prison research faces ethical hurdles, often stemming from prison conditions rather than scientific misconduct. Restrictive regulations may halt vital drug addiction studies, potentially leading to uninformed patient trials.

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    Area of Science:

    • Medical Ethics
    • Clinical Pharmacology
    • Criminology

    Background:

    • Prison research objections frequently arise from general opposition to prison conditions, not specific ethical violations.
    • Historical atrocities, such as those in Nazi prison camps, and general prison life concerns overshadow ethical considerations in research policy.
    • The National Commission's guidelines on prison research, while acknowledging ethical feasibility and prisoner willingness, impose unrealistic conditions.

    Purpose of the Study:

    • To analyze the impact of current ethical guidelines on the feasibility of conducting research within correctional facilities.
    • To highlight the potential loss of valuable research opportunities, particularly in the field of addiction studies.
    • To critique the unintended consequences of regulatory stipulations that may hinder scientific advancement.
    Keywords:
    National Commission for the Protection of Human Subjects

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    Main Methods:

    • Analysis of National Commission pronouncements on prison research ethics.
    • Evaluation of the practical implications of stipulated prison research conditions.
    • Assessment of the unique role of correctional facilities in specific research areas, such as addiction liability prediction.

    Main Results:

    • The National Commission's stringent, yet unrealistic, conditions effectively eliminate ethical prison research.
    • Prisoner volunteers express resentment at being excluded from research participation.
    • The Addiction Research Center in Lexington faces potential closure, jeopardizing critical drug addiction studies.

    Conclusions:

    • Current regulations, despite acknowledging ethical research is possible, create insurmountable barriers to prison-based studies.
    • The de facto elimination of prison research risks a return to less controlled, potentially unethical drug testing on unsuspecting patients.
    • Loss of facilities like the Addiction Research Center impedes the accurate assessment of new drug addiction potential, impacting public safety.