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Pharmacokinetics of ketoprofen in the donkey (Equus asinus)
M Oukessou1, M Bouljihad, F Van Gool
1Institut Agronomique et Vétérinaire Hassan II, Rabat, Morocco.
Zentralblatt Fur Veterinarmedizin. Reihe A
|September 1, 1996
Abstract:
The pharmacokinetic parameters of ketoprofen were determined in four donkeys after a single intravenous injection of a dose of 2.2 mg/kg body weight. The total body clearance (ClB) was 414.0 +/- 98.70 ml/h/kg (mean +/- SD), the volume of distribution at steady state (Vss) 263.10 +/- 55.43 ml/kg and the elimination half-life 1.30 +/- 0.75 h. These values were compared to those obtained in horses.