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Ex vivo Mimicry of Normal and Abnormal Human Hematopoiesis
Published on: April 10, 2012
Long-term bone marrow cultures in polycythaemia vera and essential thrombocythaemia
R Jantunen1, E Juvonen, A Aimolahti
1Department of Medicine, Helsinki University Central Hospital, Finland.
Acta Haematologica
|January 1, 1996
Abstract:
Bone marrow samples of 8 patients with essential thrombocythaemia and three patients with polycythaemia vera were cultured in long-term bone marrow cultures. The production of non-adherent cells and colony-forming unit-granulocyte-macrophage harvested weekly did not differ from that of 29 healthy bone marrow transplant donors. There was a trend towards less complete stromal confluence in patients with a myeloproliferative disease.

