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Concurrent Sweet's syndrome and Löfgren's syndrome
E Cuende Quintana1, M Gómez Rz de Mendarozqueta, M A Gorospe Arrazuria
1Rheumatology Unit, Hospital Txagorritxu, País Vasco, Spain.
The Journal of Rheumatology
|November 1, 1996
Summary
Concurrent Sweet's syndrome and Löfgren's syndrome, a form of acute sarcoidosis, are rare. This case highlights their co-occurrence, emphasizing prompt diagnosis to avoid unnecessary procedures.
Area of Science:
- Dermatology
- Rheumatology
- Pulmonology
Background:
- Sweet's syndrome is an acute febrile neutrophilic dermatosis.
- Sarcoidosis is a multisystem inflammatory disease, with Löfgren's syndrome representing an acute presentation.
- Concurrent presentation of these conditions is exceptionally rare.
Observation:
- A 40-year-old woman presented with biopsy-confirmed Sweet's syndrome lesions and erythema nodosum.
- The patient also exhibited arthritis and hilar and mediastinal adenopathy, consistent with Löfgren's syndrome.
- This clinical picture suggests a potential overlap between the two conditions.
Findings:
- The case demonstrates the simultaneous occurrence of Sweet's syndrome and Löfgren's syndrome.
- Review of literature indicates a limited number of reported cases of this concurrent presentation.
- The association between Sweet's syndrome and malignancy or hematologic disorders warrants consideration, especially with hilar adenopathy.
Implications:
- Prompt recognition of Löfgren's syndrome can help avoid aggressive diagnostic procedures.
- Understanding this association is crucial for accurate diagnosis and management.
- Further research may elucidate shared pathophysiological mechanisms between these distinct conditions.