Primary amoebic meningoencephalitis after swimming in the Rio Grande

T S DeNapoli1, J Y Rutman, J R Robinson

  • 1Santa Rosa Children's Hospital, San Antonio, TX 78207-3198, USA.

Texas Medicine
|October 1, 1996
PubMed

Insights

A fatal case of primary amoebic meningoencephalitis (PAM) caused by Naegleria fowleri occurred in a child after swimming in the Rio Grande. Sewage-polluted river water is implicated as the source, highlighting risks of recreational water exposure.

Area of Science:

  • Medical Microbiology
  • Neurology
  • Public Health

Background:

  • Primary amoebic meningoencephalitis (PAM) is a rare and often fatal infection of the central nervous system.
  • Naegleria fowleri is a free-living amoeba found in warm freshwater environments.

Observation:

  • A 13-year-old male contracted PAM after swimming in the Rio Grande and a river-fed holding tank.
  • Clinical presentation and diagnostic autopsy revealed characteristic neuropathologic features of PAM.

Findings:

  • Microscopic identification of Naegleria fowleri with broad, lobate pseudopodia confirmed the diagnosis.
  • Public health investigation identified sewage-polluted Rio Grande water as the likely source of infection.
  • Warm, sluggish water with high coliform counts creates favorable conditions for Naegleria fowleri proliferation.

Implications:

  • Exposure to polluted recreational waters, such as the Rio Grande, poses a risk for Naegleria fowleri infection.
  • Timely diagnosis based on microscopic identification is crucial for potential treatment.
  • International cooperation in pollution control is essential for preventing infectious diseases along shared borders.

Related Concept Videos

Rocky Mountain Spotted Fever01:26

Rocky Mountain Spotted Fever

Rocky Mountain Spotted Fever (RMSF) is a severe tick-borne illness caused by Rickettsia rickettsii, a Gram-negative, coccobacillary bacterium. This pathogen is an obligate intracellular parasite, requiring a host cell for replication. Transmission occurs through the bite of an infected tick. In the United States, the most important vectors are Dermacentor variabilis (American dog tick) and Dermacentor andersoni (Rocky Mountain wood tick), though other tick species may also serve as vectors.
Cryptococcal Meningitis01:27

Cryptococcal Meningitis

Cryptococcal meningitis is a life-threatening opportunistic infection predominantly associated with HIV/AIDS, accounting for over 100,000 deaths annually worldwide. However, it also affects individuals with other forms of immunosuppression, including those undergoing immunosuppressive therapy, organ transplant recipients, patients with innate immunodeficiencies, and individuals with hematological disorders. The infection is caused mainly by Cryptococcus neoformans and Cryptococcus gattii,...
Toxoplasmosis01:28

Toxoplasmosis

Toxoplasmosis, a zoonotic disease caused by the protozoan Toxoplasma gondii, poses significant public health challenges globally due to its high seroprevalence and varied clinical manifestations. As an obligate intracellular parasite, T. gondii can infect all warm-blooded vertebrates, but felids are its only definitive hosts, shedding unsporulated oocysts into the environment. Humans typically acquire the infection through ingestion of tissue cysts in undercooked meat or oocysts from...
American Trypanosomiasis01:22

American Trypanosomiasis

Chagas disease, or American trypanosomiasis, is a vector-borne parasitic infection caused by Trypanosoma cruzi, a flagellated protozoan (kinetoplastid) of the family Trypanosomatidae. The disease is endemic in Latin America, although cases are increasingly reported worldwide due to human migration. Transmission most commonly occurs when feces of infected triatomine bugs contaminate bite wounds or mucosal surfaces; additional routes include congenital, transfusional, transplant-related, and oral...
Amebiasis01:28

Amebiasis

Entamoeba histolytica, a protozoan parasite, is responsible for intestinal and extraintestinal amebiasis. Though a significant proportion of infections remain asymptomatic, approximately 50 million individuals annually are estimated to present with clinical disease, resulting in up to 100,000 deaths globally. The disease burden is disproportionately high in regions with lower socioeconomic status, such as parts of India, Africa, Mexico, and Latin America.Etiology and TransmissionThe infective...
Encephalitis l: Introduction01:19

Encephalitis l: Introduction

Encephalitis is inflammation of the brain parenchyma, most often due to infections or autoimmune processes. It presents with neuropsychiatric features such as fever, altered mental status, behavioral changes, cognitive dysfunction, seizures, focal deficits, and sometimes autonomic instability. In some cases, the meninges are also involved, resulting in meningoencephalitis.Infectious CausesInfectious encephalitis is most commonly viral but can also result from bacterial, fungal, or parasitic...