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Related Experiment Video

Updated: Jan 31, 2026

A Murine Model of Dengue Virus-induced Acute Viral Encephalitis-like Disease
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[Dengue in the Americas]

P Reiter1

  • 1CDC, National Center for Infectious Diseases, San Juan Laboratories, Puerto Rico 00921-3200. ipr@cidubi2.em.cdc.gov

Bulletin De La Societe De Pathologie Exotique (1990)
|January 1, 1996
PubMed
Summary
This summary is machine-generated.

Dengue fever, particularly severe forms like dengue hemorrhagic fever, is a growing public health crisis in Central America. The re-emergence of dengue serotype 3 has contributed to increased disease severity and fatalities.

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Area of Science:

  • Epidemiology
  • Infectious Diseases
  • Public Health

Context:

  • Dengue fever is endemic in Central America, with serotypes 1, 2, and 4 circulating.
  • Serotype 3 re-emerged in Central America in 1994 after a 20-year absence.
  • Dengue has become a significant public health issue in the region over the last decade.

Purpose:

  • To analyze the epidemiological trends of dengue in Central America.
  • To highlight the impact of dengue serotype 3 re-introduction.
  • To document the increasing severity and fatality rates of dengue.

Summary:

  • Dengue serotypes 1, 2, and 4 are widespread in Central America.
  • The re-introduction of dengue serotype 3 in 1994 has coincided with a rise in dengue hemorrhagic fever and fatal cases.
  • Historical data indicates a pattern of dengue pandemics and increasing disease severity.

Impact:

  • Dengue poses a major and worsening public health challenge in Central America.
  • The resurgence of severe dengue cases necessitates urgent public health interventions.
  • Understanding these trends is crucial for effective dengue prevention and control strategies.