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Updated: Oct 13, 2026

Assessment of Maternal Vascular Remodeling During Pregnancy in the Mouse Uterus
06:55

Assessment of Maternal Vascular Remodeling During Pregnancy in the Mouse Uterus

Published on: December 5, 2015

[Central and regional hemodynamics during the physiological course of pregnancy and the systemic circulatory

A N Strizhakov, Z M Musaev

    Vestnik Rossiiskoi Akademii Meditsinskikh Nauk
    |January 1, 1996
    PubMed

    Ninety-one patients with physiological pregnancy and gestosis were studied. This included examinations of maternal central hemodynamics and Doppler study of blood flow in the system of carotids, renal artery and its branches, uterine and umbilical arteries. The volumetric maternal central hemodynamic parameters were found to increase concurrently with a reduction in peripheral vascular resistance during physiological pregnancy, which is associated with the emergence and development of a fetoplacental complex. In gestosis, there are decreases in the volumetric maternal central hemodynamic parameters and increases in peripheral vascular resistance in all the vessels under study. Clear diagnostic criteria for predicting and diagnosing gestotic complications, such as preeclampsia and eclampsia, and fetoplacental failure in time have been defined. A contribution of echocardiographic and Doppler studies is shown in the evaluation of the severity of gestosis and the efficiency of the therapy used.

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