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Updated: Oct 23, 2026

Evaluation of Respiratory System Mechanics in Mice using the Forced Oscillation Technique
Published on: May 15, 2013
[Variability of respiratory system reactions to air pollutants. Epidemiologic study of children in Cracow]
W Jedrychowski1, E Flak, E Mróz
1Katedry Epidemiologiii i Medycyny Zapobiegawczej, Collegium Medicum Uj.
Abstract:
The main purpose of the study was to corroborate the hypothesis that the history of allergic skin reactions is the marker of individual susceptibility of respiratory tract to air pollutants in children. The study has been carried out in two contrast areas of the city regarding the air pollution level. In the dirty area the annual daily mean concentrations of particulate matter was 51.5-74.5 micrograms/m3 and sulfur dioxide 58.4-73.8 micrograms/m3; in the cleaner part of the city the corresponding concentrations were 31.7 and 36.1 micrograms/m3. The medical examination of 171 children covered standardized interviews with mothers and spirometric measurements. The results obtained showed that despite the marked decline in air pollution level, the current level of common air pollutants in the city is hazardous to the health of inhabitants. The children with history of allergic skin reactions have been affected much stronger by the higher level of air pollutants than other children. Beside the higher frequency of chronic cough or phlegm, wheezing or shortness of breath, they had significantly poorer lung function measured by FEVI/FVC index.
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