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[Intracytoplasmic sperm injection and Klinefelter syndrome]
1Equipe de Biologie de la Reproduction, INSERM U 309, Institut Albert Bonniot, Faculté de Médecine de Grenoble, La Tronche.
Contraception, Fertilite, Sexualite (1992)
|July 1, 1996
Abstract:
Sperm cytogenetic study in two patients with Klinefelter's syndrome have demonstrated that there existed a risk low but highly significant, to transmit a sex chromosome abnormality to the offsprings. This result argues for a systematic karyotype before ICSI, and if such mosaïcs can be treated by ICSI, they must be firstly associated to a genetic counselling.