Related Experiment Video
Updated: Oct 2, 2026

Experimental and Imaging Techniques for Examining Fibrin Clot Structures in Normal and Diseased States
Published on: April 1, 2015
Effects of unsaturated fatty acids on blood clotting and fibrinolysis
1Department of Nutrition and Dietetics, King's College London, UK.
Abstract:
The importance of factors influencing blood clotting and fibrinolysis in preventing coronary events is now established. Modification of these factors is likely to be of more immediate benefit to an elderly population than factors influencing the atherogenic process. Although good evidence shows that intake of long chain fatty acids (> C12) is a major determinant of factor VIIc, little evidence supports the importance of the degree of unsaturation. The role of unsaturated fatty acids in thrombogenesis still remains controversial.
Related Concept Videos
Structure of Lipids
Lipid-derived Compounds in the Human Body
Fat-soluble Vitamins
Fat-soluble vitamins, including vitamins A, D, E, and K, are required in minimal quantities, but their deficiencies can lead to severely abnormal physiological conditions. For example, vitamin A deficiency can cause night blindness, dry skin, delayed...
Anticoagulant Drugs: Low-Molecular-Weight Heparins
Coagulation
During the coagulation phase, clotting factors, or procoagulants, play a vital role in initiating and progressing the coagulation cascade. This cascade is a series of reactions...
Extrinsic and Intrinsic Pathways of Hemostasis
The Extrinsic Pathway
The extrinsic pathway of coagulation is typically initiated by tissue damage that exposes blood to tissue factor (TF), a protein released by the damaged tissue cells outside the blood vessels—this interaction with TF triggers biochemical reactions involving specific clotting factors. The key player here is Factor VII, which forms a...
Clot Retraction and Fibrinolysis

