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[Postmenopausal frontal fibrosing alopecia]

R Feldmann¹, M Harms, J H Saurat

¹Universitäts-Hautklinik, Genf.

Der Hautarzt; Zeitschrift Fur Dermatologie, Venerologie, Und Verwandte Gebiete

|July 1, 1996

Summary

Frontal fibrosing alopecia (FFA) is a scarring hair loss condition affecting postmenopausal women, causing progressive frontotemporal hair recession. While its cause is unknown, the condition appears to be self-limiting, though effective treatments are still needed.

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Area of Science:

Dermatology
Pathology

Background:

Frontal fibrosing alopecia (FFA) is a recently described condition primarily affecting postmenopausal women.
It is characterized by a progressive band-like loss of hair at the frontotemporal and parietal scalp margins.

Observation:

Two cases of FFA in postmenopausal women are presented.
One patient also exhibited vulvar lichen sclerosus et atrophicus, suggesting a potential association.

Findings:

Histological examination revealed perifollicular fibrosis and lymphocytic inflammation around the follicular isthmus and infundibulum.
The alopecia presents as a symmetrical, scarring band typically 3-6 cm wide.

Implications:

Currently, no definitive treatment for FFA is established.

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The disease course appears to be self-limited, offering a degree of predictability for prognosis.