[State of autonomic regulation in patients with mitral valve prolapse and dysfunction of sinus node]

This study was made of 62 patients with idiopathic mitral prolapse, 17 patients with vagus sinus dysfunction and 8 patients with combination of the above disorders. Clinical, psychological and electrophysiological examinations revealed in all the patients psychovegetative syndrome with paroxysmal and permanent vegetative disorders, anxious-hypochondriacal and anxious-depressive conditions. Vegetative disorders were characterized by definite discoordination of vegetative regulation manifesting as hyperactivity of suprasegmental vegetative structures and insufficiency of both sympathetic and parasympathetic vegetative regulation.