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[Evaluation of antibacterial and antitoxic activity of normal human immunoglobulin for intravenous use (IVIG)]
B Bucholc1, W Banach, T Wysokińska
1Zakład Badania Surowic i Szczepionek PZH w Warszawie.
In the present study, human immunoglobulins for intravenous use (IVIG), were tested for contents of diphtheria antibodies, antistreptolysin O, antistaphylolysin and antibody level of endotoxin of B. pertussis, enterobacterial common antigen and group B Streptococci. It was shown that all examined immunoglobulin preparation contained antibodies against all tested antigens. Our investigation revealed differences between IVIG preparations and IVIG lots. Basing on these results, we know that the biological activity of Bioglobulin is the same as biological activity of other IVIG preparations produced by foreign manufactures.
In the present study, human immunoglobulins for intravenous use (IVIG), were tested for contents of diphtheria antibodies, antistreptolysin O, antistaphylolysin and antibody level of endotoxin of B. pertussis, enterobacterial common antigen and group B Streptococci. It was shown that all examined immunoglobulin preparation contained antibodies against all tested antigens. Our investigation revealed differences between IVIG preparations and IVIG lots. Basing on these results, we know that the biological activity of Bioglobulin is the same as biological activity of other IVIG preparations produced by foreign manufactures.