[Acute pancreatitis: inflammatory response of the body]

The author reviews the most important data related with the pathogenesis of pancreatitis acuta, the pathological characteristics, the clinical development of the disease, the more frequent complications are summarized. Within this scope the evolutionary mechanisms of the organ damages are discussed, the diagnostic and prognostic relations are delineated, too. Particular attention is paid to the development and regulation of the defending, preventing reactions of the organisms connected with pancreatitis acuta. The process of leukocyte emigration into the tissue being shortly summarized, the acute phase reaction of the organism and the pathophysiological, clinical significance of the acute phase reactants are likewise presented. The author deals distinctly with the physiological, pathophysiological functions of alpha 2-macroglobulin and with its significance in pancreatitis acuta. The therapeutic outlooks are in a few words touched upon. The acute phase reaction of the organism is inserted in the framework of the possible types of the protecting, preventing responses of the organism.