Related Experiment Videos
[Myofibroblastoma of the lymph nodes]
Abstract:
We report a case of intranodal myofibroblastoma occurring in a lymph node of the left inguinal region of a 53 years old female. This tumor was first described 6 years ago and has not been yet documented in the Hungarian literature. This rare benign mesenchymal neoplasm of the lymph node occurs almost exclusively in the inguinal region. Histologically the tumor is characterized by interlacing fascicles of spindle cells which show nuclear palisading and the presence of hemorrhage. Immunohistochemically, the tumor cells were positive for actin and vimentin. Electronmicroscopic investigation demonstrated features characteristic for myofibroblastic origin. Characteristic amianthoid structures were occasionally present. It is important to distinguish this tumor entity of other primary or secondary mesenchymal neoplasms of lymph nodes including nodal involvement of Kaposi's sarcoma, a lesion it may closely resemble.