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[Chronic gastritis in children: evaluation after eleven years]
E Michałowicz-Wojczyńska1, P Swiatkowski, J Orłowska
1II Oddzial Wojewódzkiego Szpitala Dziecieccgo im. J.P. Brudzińskiego w Dziekanowie Leśnym.
Insights
Childhood chronic gastritis (CG) often persists into adulthood, especially with H. pylori infection. Early H. pylori treatment in children with CG is recommended to prevent long-term complications.
Area of Science:
- Pediatric Gastroenterology
- Infectious Diseases
- Hepatology
Background:
- Chronic gastritis (CG) in children can lead to long-term health issues.
- Helicobacter pylori (H. pylori) infection is a common cause of CG.
Purpose of the Study:
- To investigate the long-term progression of childhood chronic gastritis.
- To assess the impact of H. pylori infection on the persistence of CG and related complications.
Main Methods:
- Longitudinal study of pediatric patients diagnosed with CG.
- Clinical re-examination, gastroscopy, and histopathological analysis including H. pylori testing after eleven years.
- Assessment of gastritis progression, duodenal ulcer recurrence, and treatment outcomes.
Main Results:
- 95% of patients with childhood CG remained infected with H. pylori and had persistent or progressed gastritis.
- Childhood duodenal ulcers recurred in all affected patients.
- H. pylori eradication therapy led to regression or disappearance of CG in most treated patients.
Conclusions:
- Childhood-onset H. pylori-positive chronic gastritis persists into adulthood.
- Anti-H. pylori treatment is recommended for children diagnosed with H. pylori-positive CG.
Unlabelled:
Chronic gastritis (CG) was diagnosed in 38 of 130 children with abdominal pain treated between 1980-1982. After eleven years, 20 of the 38 patients with CG were re-examined clinically and gastroscopically. Six gastric biopsies for hitopathological examination and two for CLO tests in each patient were taken. In 13 of 20 additional staining for H. pylori was done in the biopsy specimens take 11 years ago. In 95% (19 of 20) patients, CG and H. pylori infection were found. Thirteen of them (all examined) had already been infected with HP in childhood. Gastritis had progressed or remained unchanged in 90% (17 of 19) patients in the corpus and in 75% (15 of 20) in the antrum. All 6 patients who had duodenal ulcers (DU) in childhood had recurrences of DU. Thirty-one percent (4/13) of patients with persisting CG that had no ulcers previously, now had DU or erosions. All 19 patients with CG and HP infection received triple therapy. In 6 of 7 those regression or disappearance of CG and HP eradication were seen re-examined.
Conclusions:
CG which began in childhood progresses or persists until adulthood in all H. pylori - positive patients. We suggest that children with H. pylori-positive CG should receive anti-H. pylori treatment.