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[Results of thrombolytic therapy with streptokinase for chronic deep vein thrombosis]
J Kładny1, G Szumiłowicz, P Gutowski
1Kliniki Chirurgii Ogólnej i Naczyniowej w Szczecinie.
Insights
Intravenous streptokinase treatment showed potential efficacy in long-lasting deep vein thrombosis (DVT). This study explored its effectiveness in patients with partially or entirely occluded deep veins, suggesting benefits even weeks after symptom onset.
Area of Science:
- Vascular Medicine
- Thrombosis Research
- Pharmacology
Abstract:
69 patients with DVT at least 1 week after acute symptoms was treated with streptokinase (Mean time 4 weeks after acute symptoms). Patients was divided for two groups: 1. with not entire main segments of deep vein occlusion and 2. with entire occlusion of segments of deep vein. Estimation of thrombolytic efficacy was performed by C. Theory. In the 1. group we achieved 23.8% of total obliteration and in 28.6% not entire. In the group 2. we achieved only 24.9% of partial obliteration. Intravenous streptokinase could be effective as well in long lasting deep vein thrombosis.