[Ultrastructural studies of the detrusor in patients with benign prostatic hyperplasia]

Unstable bladder was diagnosed in 15.9% of patients with post-operative problems with urination. It is suggested that the mechanism of urination defects in patients with benign prostatic hyperplasia may imply not only mechanical compression, stretching of the posterior urethra, changes in the urethrovesical angle, but also detrusor abnormalities. Ultrastructure of bladder muscles was studied in 6 patients with benign prostatic hyperplasia. In all cases bladder tissue underwent dystrophic, hypertrophic or atrophic changes. Lesions of the contractile apparatus of the bladder were associated with microcirculatory vessels sclerosis. The above ultrastructural alterations should be considered in combined therapy of patients with benign prostatic hyperplasia.