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Related Concept Videos

Infection01:20

Infection

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When a pathogen enters the body and reproduces, it can cause an infection, damage body cells, and cause illness symptoms that eventually lead to disease. Therefore, its prevention requires breaking the chain of infection.
The chain begins with pathogens: bacteria, viruses, fungi, prions, or parasites such as protozoa helminths. These can be present on the skin as transient or resident flora, or they can be acquired from the environment. Identifying and treating the type of infection and...
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Factors Affecting the Risk of Infection01:26

Factors Affecting the Risk of Infection

14.1K
The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
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Skin Diseases and Disorders01:23

Skin Diseases and Disorders

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Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
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Sexually Transmitted Infections01:26

Sexually Transmitted Infections

2.0K
Sexually transmitted infections (STIs) are diseases transmitted primarily through unsafe sexual interactions. Bacteria, viruses, or parasites cause them and can result in severe health complications if untreated.ChlamydiaThe bacterium Chlamydia trachomatis is responsible for the disease Chlamydia, the most common STI in the United States. This peculiar pathogen requires human cells to reproduce, residing intracellularly. The initial infection often goes unnoticed because it typically does not...
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Infectious Diseases and Their Occurrence01:28

Infectious Diseases and Their Occurrence

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Infectious diseases appear in populations through various transmission patterns, influenced by pathogen characteristics, population immunity, environmental conditions, and social behavior. Understanding these patterns is essential for effective public health surveillance and intervention. These categories—sporadic, outbreak, epidemic, pandemic, and endemic—help frame the nature and scope of disease events.Sporadic diseases occur irregularly and infrequently, without a predictable...
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Reservoir of Infection01:30

Reservoir of Infection

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Infectious diseases arise from intricate interactions between pathogens and their reservoirs. A reservoir of infection refers to the natural habitat where a pathogen lives, grows, and multiplies, serving as a continual source of infection. Reservoirs are broadly classified as either living or nonliving, and each plays a unique role in disease transmission, significantly influencing public health interventions and control strategies.Humans act as reservoirs for a wide array of pathogens,...
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Tractable Mammalian Cell Infections with Protozoan-primed Bacteria
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Tractable Mammalian Cell Infections with Protozoan-primed Bacteria

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Are all diseases infectious?

B Lorber1

  • 1Section of Infectious Diseases, Temple University Hospital, Philadelphia, PA 19140, USA.

Annals of Internal Medicine
|November 15, 1996
PubMed
Summary
This summary is machine-generated.

Emerging infectious diseases are gaining attention, but a fundamental shift reveals transmissible agents also cause non-infectious diseases like cancer. This broadens our understanding of host-pathogen interactions.

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Area of Science:

  • Microbiology
  • Immunology
  • Pathogenesis

Background:

  • Human-microorganism interactions encompass infectious diseases and symbiotic relationships with normal flora.
  • Recent media focus highlights emerging infectious diseases like Ebola virus hemorrhagic fever.
  • A paradigm shift is occurring in understanding host-pathogen interactions beyond traditional infectious diseases.

Purpose of the Study:

  • To highlight the evolving understanding of human-microorganism interactions.
  • To underscore the role of transmissible agents in diseases not traditionally considered infectious.
  • To explore new avenues for disease prevention through immunization.

Main Methods:

  • Review of current literature on infectious and non-infectious diseases.
  • Analysis of media reporting trends on emerging infectious diseases.
  • Examination of established and novel host-pathogen interactions.

Main Results:

  • Transmissible agents are implicated in a growing number of diseases previously not suspected of infectious origins.
  • Examples include ulcer disease, neurodegenerative disorders, inflammatory conditions, and cancers.
  • This expanded view challenges traditional disease classifications.

Conclusions:

  • The definition of infectious disease is broadening due to new discoveries.
  • Host-pathogen interactions offer novel targets for therapeutic and preventative strategies, particularly immunization.
  • Further research into these complex interactions is crucial for public health.