Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

IL-4 in schistosomiasis

E J Pearce1, J P Vasconcelos, L R Brunet

  • 1Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, New York 14853, USA.

Experimental Parasitology
|November 1, 1996
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Helminth infection reactivates latent γ-herpesvirus via cytokine competition at a viral promoter.

Science (New York, N.Y.)·2014
Same author

Imaging trematode and nematode parasites.

Parasite immunology·2013
Same author

Veterinary education: a basis for good governance leading to effective veterinary services.

Revue scientifique et technique (International Office of Epizootics)·2013
Same author

An intra-patient placebo-controlled phase I trial to evaluate the safety and tolerability of intradermal IMM-101 in melanoma.

Annals of oncology : official journal of the European Society for Medical Oncology·2011
Same author

IL-4(-/-) mice with lethal Mesocestoides corti infections--reduced Th2 cytokines and alternatively activated macrophages.

Parasite immunology·2009
Same author

Reverse genetics and the study of the immune response to schistosomes.

Parasite immunology·2008
Same journal

Morphological and infection responses of Psoroptes ovis var. cuniculi to Metarhizium pingshaense and peppermint-based compounds.

Experimental parasitology·2026
Same journal

Exploring polyporphyrin isolated from Carica papaya seed oil in the control of Anopheles gambiae (Diptera: Culicidae) () mosquito.

Experimental parasitology·2026
Same journal

Trypanocidal activity of nanoemulsion loaded with triterpene 3β,6β,16β-trihydroxylup-20(29)-ene from Combretum leprosum against Trypanosoma cruzi Y strain.

Experimental parasitology·2026
Same journal

Nanotechnology in the management of neglected protozoan diseases: Current advances, translational challenges, and future prospects.

Experimental parasitology·2026
Same journal

Corrigendum to "Expression profiling of GP63 isoforms with predicted nuclear localization signals in Leishmania (Viannia) braziliensis" [Experimental Parasitology 286 (2026) 109155].

Experimental parasitology·2026
Same journal

Identification of ZINC database-derived antitrypanosomal candidates targeting Trypanosoma congolense lysosomal-α-mannosidase using computational, biochemical and in vivo methods.

Experimental parasitology·2026
See all related articles

Interleukin-4 (IL-4) plays a key role in the immune response to Schistosoma mansoni infection. This review highlights recent findings from mouse models investigating IL-4's function.

Area of Science:

  • Immunology
  • Parasitology
  • Helminth infections

Background:

  • Schistosoma mansoni is a parasitic trematode causing schistosomiasis.
  • Immune responses are critical for controlling parasite burden and pathology.
  • Interleukin-4 (IL-4) is a key cytokine involved in immune regulation.

Purpose of the Study:

  • To review the role of IL-4 in the immune response to Schistosoma mansoni.
  • To emphasize recent research findings from mouse models.

Main Methods:

  • Review of existing literature.
  • Analysis of recent experimental data from mouse models of Schistosoma mansoni infection.

Main Results:

  • IL-4 influences the development of protective and pathological immune responses.

Related Experiment Videos

  • Specific findings regarding IL-4's impact on T-cell differentiation and antibody production are discussed.
  • The context-dependent effects of IL-4 in this model are highlighted.

    • Conclusions:

    • IL-4 is a critical modulator of the immune response during Schistosoma mansoni infection.
    • Understanding IL-4's function is essential for developing effective therapies against schistosomiasis.
    • Further research in mouse models will continue to elucidate IL-4's complex role.