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Related Experiment Videos

Improving drug use in rheumatic disorders

G M Peterson1, J K Bergin, B J Nelson

  • 1Tasmanian School of Pharmacy, Faculty of Medicine and Pharmacy, University of Tasmania, Hobart Tas, Australia.

Journal of Clinical Pharmacy and Therapeutics
|August 1, 1996
PubMed
Summary
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Pharmacist-led academic detailing improved prescribing of nonsteroidal anti-inflammatory drugs (NSAIDs) in community settings. This educational intervention demonstrated a significant reduction in NSAID dispensing ratios compared to paracetamol in Southern Tasmania.

Area of Science:

  • Pharmacology
  • Public Health
  • Health Services Research

Background:

  • Gastrointestinal bleeding is a significant concern in elderly patients, with nonsteroidal anti-inflammatory drugs (NSAIDs) identified as a contributing factor.
  • Approximately 50 elderly individuals are hospitalized annually in Tasmania for NSAID-related gastrointestinal bleeding.
  • There is a need to optimize NSAID prescribing practices in community settings to mitigate associated risks.

Purpose of the Study:

  • To evaluate the effectiveness of pharmacist-led academic detailing in modifying NSAID prescribing practices among general practitioners.
  • To assess whether this intervention could encourage a more rational approach to NSAID use in the community.

Main Methods:

  • An intervention study was conducted in Southern Tasmania, with the north of the state serving as a control.

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  • General practitioners in the intervention area received educational materials and direct consultation from a pharmacist on rational NSAID prescribing.
  • Pharmacoepidemiological data, including dispensed defined daily doses (DDDs) of NSAIDs versus paracetamol, were analyzed from community pharmacy records and government schemes.
  • Main Results:

    • The educational program was well-received by general practitioners.
    • Prescribing changes were observed in both regions, with a more pronounced improvement in the intervention area.
    • The ratio of dispensed DDDs of NSAIDs to paracetamol decreased from 3.00 to 2.59 in the intervention region, compared to a smaller decrease from 3.16 to 2.92 in the control region.

    Conclusions:

    • Pharmacist-led academic detailing is an effective strategy for modifying community-based NSAID prescribing practices.
    • This intervention shows promise in promoting rational NSAID use and potentially reducing associated adverse events like gastrointestinal bleeding.