Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Errors evolution and analysis in antineoplastic drug preparation during one year

M C Escoms1, M J Cabañas, M Oliveras

  • 1Pharmacy Service, Hospital Materno-infantil Vall d'Hebron, Barcelona, Spain.

Pharmacy World & Science : PWS
|October 1, 1996
PubMed
Summary

Errors in cytotoxic mixture preparation are low and decreasing. Increased daily preparation volume does not solely cause more errors in this process.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Maintained susceptibility to fosfomycin in extra-hospitalary urinary isolates of Escherichia coli. Strong association of fosfomycin resistance with age and ESBL production.

Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia·2024
Same author

Laparoscopic sleeve gastrectomy after endoscopic sleeve gastroplasty: Feasible or dangerous revisional surgery?

Cirugia espanola·2023
Same author

Intestinal perforation after pediatric liver transplantation: risk factors and management.

Cirugia pediatrica : organo oficial de la Sociedad Espanola de Cirugia Pediatrica·2023
Same author

In silico prediction of the enzymes involved in the degradation of the herbicide molinate by Gulosibacter molinativorax ON4<sup>T</sup>.

Scientific reports·2022
Same author

Interplay between psychosocial and heart failure related factors may partially explain limitations in self-efficacy in patients with heart failure: Insights from a real-world cohort of 1,123 patients.

International journal of nursing studies·2022
Same author

Discovery of serum biomarkers for diagnosis of tuberculosis by NMR metabolomics including cross-validation with a second cohort.

Biomedical journal·2021

Area of Science:

  • Pharmaceutical Sciences
  • Quality Control
  • Healthcare Management

Background:

  • The Centralized Cytotoxic Preparation Unit (CCPU) handles complex medication preparation.
  • Ensuring accuracy and safety in cytotoxic drug compounding is critical for patient outcomes.
  • Identifying and mitigating errors in preparation circuits is essential for quality assurance.

Purpose of the Study:

  • To analyze the types and frequency of errors in cytotoxic mixture preparation over one year.
  • To investigate the evolution of errors across various controlled parameters.
  • To determine factors influencing error rates in the preparation process.

Main Methods:

  • A retrospective analysis of 4,734 cytotoxic preparations was conducted over 12 months.

Related Experiment Videos

  • Twenty parameters susceptible to error within the preparation circuit were monitored.
  • Errors were defined as data absence or mistakes in controlled parameters.

    • Main Results:

    • A total of 314 errors were identified across 94,680 analyzed parameters.
    • The error percentage per parameter decreased from 0.74% in the first month to 0.26% in the last.
    • The number of daily preparations did not consistently correlate with the number of errors.

    Conclusions:

    • The error rate in cytotoxic mixture preparation is low and shows a downward trend.
    • Quality control measures appear effective in reducing preparation errors over time.
    • Preparation volume is not the sole determinant of error occurrence; other factors likely play a role.