Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Initial experience with a new, partially covered Wallstent for malignant biliary obstruction

P Born1, H Neuhaus, T Rösch

  • 1Second Medical Clinic, Klinikum rechts der Isar, Technical University of Munich, Germany.

Endoscopy
|October 1, 1996
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Zeitschrift fur Gastroenterologie·2022
Same author

Zeitschrift fur Gastroenterologie·2021
Same author

Histopathological Analysis of PEEK Wear Particle Effects on the Synovial Tissue of Patients.

BioMed research international·2016
Same author

[Not Available].

Zeitschrift fur Gastroenterologie·2016
Same author

Endoscopic therapy for infected pancreatic necrosis using fully covered self-expandable metal stents: combination of transluminal necrosectomy, transluminal and percutaneous drainage.

Zeitschrift fur Gastroenterologie·2016
Same author

[Evaluation of endoscopic live case demonstrations--the patient's and participant's perspective].

Zeitschrift fur Gastroenterologie·2015

Covered metal biliary stents show promise in preventing tumor ingrowth, but require further development to improve functionality and reduce complications like occlusion and dislocation in patients with malignant biliary obstruction.

Area of Science:

  • Gastroenterology
  • Interventional Endoscopy
  • Oncology

Background:

  • Metal biliary stents offer improved patency over plastic stents but are susceptible to tumor ingrowth.
  • Tumor ingrowth through mesh remains a significant challenge in managing malignant biliary obstruction.

Purpose of the Study:

  • To evaluate the preliminary clinical experience with partially covered metal stents in patients with malignant biliary obstruction.
  • To assess the safety and efficacy of covered metal stents in preventing tumor ingrowth and maintaining patency.

Main Methods:

  • A prospective study involving ten patients with malignant biliary obstruction who received partially covered Wallstents.
  • Patients were followed for one year with clinical assessments, laboratory tests, imaging, and telephone interviews.

Related Experiment Videos

Main Results:

  • Stent insertion was technically successful, significantly reducing bilirubin levels.
  • Mean survival was 7.5 months post-diagnosis; two patients survived beyond 12 months.
  • Four patients experienced stent dysfunction (occlusion or dislocation), with a correlation noted between stent diameter and dysfunction.

Conclusions:

  • Partially covered biliary metal stents represent a potential strategy to mitigate tissue ingrowth.
  • Current stent designs require further refinement to enhance durability and minimize complications for effective long-term use.