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Updated: Aug 7, 2026

Experimental Human Pneumococcal Carriage
Published on: February 15, 2013
Management of healthcare workers with pharyngitis or suspected streptococcal infections
D J Weber1, W A Rutala, F W Denny
1Adult Division of Infectious Diseases, University of North Carolina School of Medicine, Chapel Hill, USA.
Abstract:
The group A streptococcus may cause pharyngitis, rheumatic fever, streptococcal toxic shock syndrome, and serious skin and soft-tissue infections. More than 50 nosocomial outbreaks have been reported since 1966. For this reason, healthcare facilities should develop policies for the diagnosis and treatment of symptomatic hospital employees, and for the recognition and management of potential outbreaks. The clinical diagnosis of streptococcal pharyngitis is unreliable. Rapid streptococcal tests may be used for initial screening, but a negative rapid test should be confirmed with a properly obtained culture. Penicillin remains the treatment of choice, but new alternatives now include a 5-day course of either azithromycin or cefpodoxime.
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