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Type I second-degree AV block after neostigmine administration in a child with renal failure
1Department of Pediatric Dentistry, Baylor College of Dentistry, Dallas, Texas 75246, USA.
Anesthesia Progress
|January 1, 1995
Abstract:
Neostigmine is commonly used to reverse neuromuscular blockade. A side effect can be parasympathetic stimulation, which may result in heart block. Renal failure can decrease the clearance and increase the half-life of the drug, thus increasing the likelihood of a vagomimetic response. A case is presented where a child with renal failure developed a type I second-degree heart block after neostigmine was given.