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Tuberculous pericarditis

K S Kutoloski¹, T J Salvucci, C Dennis

¹Department of Cardiology, Deborah Heart and Lung Center, Brown Mills, NJ, USA.

The Journal of the American Osteopathic Association

|April 1, 1996

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Tuberculosis can cause severe pericardial effusion and constriction, requiring extensive surgery. Early diagnosis of this rare condition remains challenging, despite advances in treatment.

Area of Science:

Infectious Diseases
Cardiology
Pulmonology

Background:

Pericardial effusion and constriction are serious complications of extrapulmonary tuberculosis.
Steroid treatment is often ineffective for tuberculous pericarditis.

Observation:

A patient presented with persistent pericardial effusion and constriction despite initial surgery and treatment for Mycobacterium tuberculosis.
Echocardiography revealed decreased left ventricular function, necessitating further surgical intervention.

Findings:

Histologic examination confirmed severe granulomatous pericarditis due to Mycobacterium tuberculosis.
A rare extrapulmonary tuberculosis led to constrictive pericarditis, complicated by bilateral pleural effusions post-surgery.

Implications:

Related Experiment Videos

Early diagnosis of tuberculous pericarditis is crucial but challenging due to non-specific findings and diagnostic delays.
Aggressive surgical management combined with antituberculous therapy can improve outcomes, but mortality remains significant.
This case highlights the importance of considering tuberculosis in unexplained pericardial disease, even with negative tuberculin tests.