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Related Experiment Videos

Evaluation of patch testing in patients with chronic vulvar symptoms

J A Brenan1, G J Dennerstein, S F Sfameni

  • 1Dermogynaecology Clinic, Mercy Hospital for Women, Melbourne, Victoria, Australia.

The Australasian Journal of Dermatology
|February 1, 1996
PubMed
Summary

Contact allergy is a significant cause of dermatitis in women. Patch testing revealed nickel, fragrances, and medicaments as common allergens, indicating the need for careful allergen avoidance in dermatological care.

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Area of Science:

  • Dermatology
  • Allergology
  • Clinical Medicine

Background:

  • The Dermogynaecology Clinic at Mercy Hospital for Women has investigated 700 patients since 1989.
  • Fifteen percent of patients were clinically diagnosed with contact dermatitis.

Purpose of the Study:

  • To investigate the prevalence and causes of contact allergy in patients presenting with dermatitis.
  • To identify common allergens responsible for allergic contact dermatitis in this patient cohort.

Main Methods:

  • Fifty patients underwent patch testing with a standard battery, medicaments, preservatives, corticosteroids, and miscellaneous allergens.
  • Analysis of positive patch test reactions to identify specific allergens.

Main Results:

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  • Twenty-one patients (42%) showed positive reactions to allergens.
  • The most frequent positive reactions were to nickel (22%), fragrances (12%), and ethylenediamine (8%).
  • Medicaments and fragrances were identified as significant allergens.

    • Conclusions:

    • Contact allergy is a notable factor in dermatitis among patients seen at the clinic.
    • Nickel, fragrances, and medicaments are key allergens requiring attention in clinical practice.
    • Corticosteroid and imidazole allergy were not significant issues in this patient group.