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Related Experiment Videos

Renal replacement therapy in the elderly

C M Mandigers1, W de Jong, A W van den Wall Bake

  • 1Department of Medicine, St. Joseph Hospital, Veldhoven, Netherlands.

The Netherlands Journal of Medicine
|October 1, 1996
PubMed
Summary
This summary is machine-generated.

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Elderly patients undergoing renal replacement therapy (RRT) show acceptable survival and quality of life. Age and comorbidities should not prevent RRT initiation for older adults with kidney failure.

Area of Science:

  • Nephrology
  • Geriatrics
  • Internal Medicine

Background:

  • Renal replacement therapy (RRT) is a critical treatment for end-stage kidney disease.
  • The decision to initiate RRT in elderly patients involves considerations of survival and quality of life.
  • Limited data exists on long-term outcomes for this specific demographic.

Purpose of the Study:

  • To evaluate survival and identify factors influencing outcomes in elderly patients commencing RRT.
  • To assess the impact of age and comorbidities on RRT effectiveness in older adults.
  • To determine the safety and efficacy of RRT in the geriatric population.

Main Methods:

  • Retrospective analysis of medical records for 122 patients aged over 65 years at RRT initiation.
  • Data collected included patient demographics, RRT modality, comorbidities, and survival status.

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  • Statistical analysis to compare survival rates across different patient groups and treatment modalities.

    • Main Results:

    • Mean age at RRT start was 72.7 years; 76% received hemodialysis.
    • Median survival was 23.8 months, with 2-year survival at 50%.
    • Younger elderly (65-75) had longer survival (36.4 months) than older (12.5 months). Comorbidities like COPD and PVD reduced survival; tubulo-interstitial nephritis improved it.

    Conclusions:

    • Survival and quality of life in elderly patients on RRT are acceptable.
    • Age and comorbidities should not be absolute contraindications for RRT in the elderly.
    • RRT can be a viable option for older adults with kidney failure, improving outcomes.