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Related Experiment Videos

Total capsular calcification in a prolactinoma--case report

T Horiuchi1, Y Tanaka, S Kobayashi

  • 1Department of Neurosurgery, Suwa Red Cross Hospital, Nagano, Japan.

Neurologia Medico-Chirurgica
|October 1, 1996
PubMed
Summary

A pituitary adenoma with unusual calcification was incidentally discovered. This rare presentation, likely due to tumor degeneration, highlights atypical radiological features of prolactinomas.

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Area of Science:

  • Endocrinology
  • Neuroimaging
  • Pathology

Background:

  • Pituitary adenomas are common tumors, but atypical presentations require careful radiological and pathological evaluation.
  • Prolactinomas are the most frequent type of pituitary adenoma, typically presenting with hyperprolactinemia symptoms.

Observation:

  • A 42-year-old male incidentally found to have a cystic pituitary tumor with an egg-shell calcification on CT and an enlarged, partially empty sella turcica on MRI.
  • Operative findings confirmed a cystic tumor encased in a calcified shell.
  • Immunohistochemistry revealed prolactin-positive cells, confirming a prolactin-producing pituitary adenoma.

Findings:

  • The radiological findings, including extensive calcification and an enlarged, partially empty sella turcica, were atypical for a pituitary adenoma.

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  • The combination of imaging features and operative findings suggested spontaneous tumor degeneration as the cause of the unusual presentation.

    • Implications:

    • This case underscores the importance of considering rare radiological appearances in pituitary adenomas.
    • Spontaneous degeneration should be included in the differential diagnosis for cystic pituitary lesions with calcification.
    • Further research into the mechanisms of pituitary adenoma degeneration could improve diagnostic accuracy and treatment strategies.