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Lithium and male sexual function in affective patients
D Aizenberg1, M Sigler, Z Zemishlany
1Geha Psychiatric Hospital, Beilinson Medical Center, Petah Tikva, Israel.
Clinical Neuropharmacology
|December 1, 1996
Summary
Lithium treatment in men with bipolar or schizoaffective disorder may affect sexual desire and arousal. However, most patients reported preserved sexual pleasure and satisfaction, with no distress or noncompliance.
Area of Science:
- Psychiatry
- Pharmacology
- Sexual Medicine
Background:
- Lithium is a common mood stabilizer for bipolar and schizoaffective disorders.
- Sexual dysfunction is a potential side effect of psychotropic medications.
- The impact of lithium on male sexual function requires further investigation.
Purpose of the Study:
- To evaluate sexual function and behavior in male patients undergoing lithium therapy.
- To determine the prevalence and nature of sexual dysfunction in this population.
- To assess the relationship between lithium levels and sexual function.
Main Methods:
- A study involving 35 male patients with bipolar or schizoaffective disorder on lithium monotherapy.
- Assessment of sexual function using a standardized questionnaire.
- Measurement of serum lithium levels.
Main Results:
- 31.4% of patients reported sexual dysfunction.
- Common issues included reduced sexual thoughts (23%) and erectile difficulties (20%).
- Despite dysfunction, most patients reported preserved pleasure and satisfaction with sexual activity.
Conclusions:
- Lithium therapy may impact sexual desire and arousal but not significantly affect overall satisfaction or pleasure.
- Sexual dysfunction in this study did not lead to patient distress or treatment noncompliance.
- Serum lithium levels did not correlate with sexual function outcomes.