Clinical cancer research--some aspects on doctors' attitudes to informing participants

With the aim to investigate the information policy of oncologists when recruiting patients for clinical trials a postal questionnaire was sent to 412 members of the Swedish Society of Oncology (response rate 74%). Depending on the situation, 20-40% of the doctors perceive that randomization before consent is an acceptable procedure. A majority of the physicians maintain that cancer patients are able to cope with adequate information but 45% of the doctors fear that the patients may withdraw from participating if they are adequately informed. It seems to be important to study the relationship between the quality of information given to participants and the motives they have for accepting or declining to participate.