Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

A receiver operating characteristic partial area index for highly sensitive diagnostic tests

Y Jiang1, C E Metz, R M Nishikawa

  • 1Department of Radiology, Kurt Rossmann Laboratories for Radiologic Image Research, University of Chicago, IL 60637, USA.

Radiology
|December 1, 1996
PubMed
Summary

A new partial area index offers a more meaningful measure of diagnostic performance than the traditional Area under the receiver operating characteristic curve (Az) for tests prioritizing high sensitivity.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Using breast radiographers' reports as a second opinion for radiologists' readings of microcalcifications in digital mammography.

The British journal of radiology·2014
Same author

Validation of a power-law noise model for simulating small-scale breast tissue.

Physics in medicine and biology·2013
Same author

Scanning translucent glass-ceramic x-ray storage phosphors.

Proceedings of SPIE--the International Society for Optical Engineering·2012
Same author

Automated detection of mass lesions in dedicated breast CT: a preliminary study.

Medical physics·2012
Same author

On the orientation of mammographic structure.

Medical physics·2011
Same author

Task-based assessment of breast tomosynthesis: effect of acquisition parameters and quantum noise.

Medical physics·2010

Area of Science:

  • Medical Diagnostics
  • Biostatistics
  • Radiology

Background:

  • The Area under the receiver operating characteristic curve (Az) is a common metric for diagnostic test performance.
  • Az may not accurately reflect clinical utility when high sensitivity is paramount.

Purpose of the Study:

  • To develop and validate a novel ROC partial area index.
  • This index specifically measures diagnostic performance in high-sensitivity regions.

Main Methods:

  • The partial area index was mathematically derived from the binormal model.
  • Statistical tests for the index were developed, mirroring those for Az.
  • A common statistical test was validated using computer simulations.

Main Results:

Related Experiment Videos

  • The partial area index provides a more clinically relevant summary of diagnostic performance in high-sensitivity scenarios.
  • Mammography example demonstrates the superiority of the partial area index over Az.

Conclusions:

  • The ROC partial area index is a valuable alternative to Az for diagnostic tests requiring high sensitivity.
  • This new index enhances the meaningful assessment of clinical diagnostic performance.