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Matrix metalloproteinases and the development of cancer
1Department of Biochemistry and Biophysics, University of California, San Francisco, California 94143-0534, USA.
Chemistry & Biology
|November 1, 1996
Abstract:
Proteolytic remodeling of the extracellular matrix is an important aspect of the creation and progression of cancer. Matrix metalloproteinases are important at several points during multi-stage neoplastic progression in tumor cells and responding blood vessels, inflammatory cells and stroma.