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Drug-related killings: a case of mistaken identity
1Imperial Cancer Research Fund, Clare Hall Laboratories, South Mimms Herts., UK.
Chemistry & Biology
|November 1, 1996
Abstract:
Abortive attempts at DNA repair can contribute to the effects of DNA damage inflicted by cytotoxic drugs. DNA methylation damage, 6-thioguanine and cisplatin adducts all owe their cytotoxicity in part to the intervention of DNA mismatch repair.