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Related Experiment Videos

Melioidosis presenting with orbital cellulitis

P K Wong1, P H Ng

  • 1Department of Ophthalmology, National University Hospital, Singapore.

Singapore Medical Journal
|April 1, 1996
PubMed
Summary

Melioidosis, a bacterial infection, can cause rare orbital cellulitis. This case highlights a fatal outcome despite early treatment, emphasizing the disease

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Area of Science:

  • Infectious Diseases
  • Ophthalmology
  • Medical Microbiology

Background:

  • Melioidosis (caused by Burkholderia pseudomallei) presents with diverse clinical manifestations.
  • Orbital cellulitis is a known ophthalmic emergency, typically caused by bacterial infections.
  • The association between melioidosis and orbital cellulitis has not been previously documented.

Observation:

  • A 42-year-old male with diabetes mellitus presented with symptoms of orbital cellulitis.
  • The patient's condition rapidly progressed despite initiation of antibiotic therapy.

Findings:

  • The patient was diagnosed with melioidosis, complicated by orbital cellulitis.
  • Despite early antibiotic intervention, the patient experienced recurrent paranasal sinus empyema, rupture of an intracranial mycotic aneurysm, and pulmonary empyema.
  • The patient ultimately succumbed to the severe complications of melioidosis.

Implications:

  • This case report describes the first instance of orbital cellulitis secondary to melioidosis.
  • It underscores the potential for unusual presentations of melioidosis, even in patients receiving prompt treatment.
  • Highlights the critical need for considering melioidosis in the differential diagnosis of orbital cellulitis, particularly in endemic areas or in patients with risk factors like diabetes.

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