Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Flap selection in cranial base reconstruction

P C Neligan1, S Mulholland, J Irish

  • 1Head and Neck Program, Toronto Hospital, Ontario, Canada.

Plastic and Reconstructive Surgery
|December 1, 1996
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Localization of the CHIP28 water channel in rat kidney.

The American journal of physiology·1992
Same author

Relationship between CNV asymmetries and individual differences in cognitive performance, personality and gender.

International journal of psychophysiology : official journal of the International Organization of Psychophysiology·1992
Same author

Directional instability of microtubule transport in the presence of kinesin and dynein, two opposite polarity motor proteins.

The Journal of cell biology·1992
Same author

Expression of mRNA (D2) encoding a protein involved in amino acid transport in S3 proximal tubule.

The American journal of physiology·1992
Same author

A comparison of external rate responsive pacemakers with identical implanted units.

Pacing and clinical electrophysiology : PACE·1992
Same author

Improved diagnosis of chronic hepatitis C virus infection by detection of antibody to multiple epitopes: confirmation by antibody to synthetic oligopeptides.

Journal of medical virology·1992
Same journal

Building Practical Artificial Intelligence Tools For The Plastic Surgeon: A Step-By-Step Guide To Cowork.

Plastic and reconstructive surgery·2026
Same journal

Interpretation Matters: Common Statistical Pitfalls in Retrospective Surgical Research.

Plastic and reconstructive surgery·2026
Same journal

"Inferior Repositioning of the High-Riding Nipple Using a Parenchymal-Based Flap".

Plastic and reconstructive surgery·2026
Same journal

A Four-Step Strategy for the Treatment of Facial Rhytids: A Focus on Upper Facial Wrinkles.

Plastic and reconstructive surgery·2026
Same journal

Evaluating Long-Term Retention of Fresh-Frozen Costal Cartilage Allograft in An Animal Model.

Plastic and reconstructive surgery·2026
Same journal

Manual extrusion of fat granules for primary thinning of a bulky flap.

Plastic and reconstructive surgery·2026
See all related articles

Free-flap reconstructions offer superior outcomes for skull base defects, demonstrating better wound healing and fewer complications than pedicled flaps. Microvascular free-tissue transfer is recommended for moderate to large cranial base reconstructions.

Area of Science:

  • Plastic Surgery
  • Neurosurgery
  • Craniofacial Reconstruction

Background:

  • Skull base defects pose significant reconstruction challenges.
  • Traditional methods include pericranial flaps and pedicled myocutaneous flaps.

Purpose of the Study:

  • To compare the efficacy of local, pedicled, and free-flap reconstructions for skull base defects.
  • To identify the safest and most economical reconstruction method.

Main Methods:

  • Retrospective analysis of 90 skull base defect reconstructions over 10 years.
  • Comparison of outcomes between pericranial, pedicled myocutaneous, and free-flap techniques.

Main Results:

  • Pericranial flaps provided reliable dural sealing.

Related Experiment Videos

  • Free-flap reconstructions showed higher uncomplicated primary wound healing (95% vs. 62.5%).
  • Free flaps had significantly lower rates of flap loss (0%), CSF leak (5%), meningitis, and abscess (0%).
  • Conclusions:

    • Microvascular free-tissue transfer is the safest and most economical option for moderate to large composite skull base defects.
    • Free-flap reconstruction offers superior outcomes compared to pedicled myocutaneous flaps.