Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Microbial evaluation: 139 implants removed from symptomatic patients

C Y Ahn1, C Y Ko, E A Wagar

  • 1Division of Plastic and Reconstructive Surgery, UCLA School of Medicine, USA.

Plastic and Reconstructive Surgery
|December 1, 1996
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Dynamics of childhood obesity in Hong Kong throughout the COVID-19 pandemic before and after the school closures: a 3-year longitudinal study.

Public health·2023
Same author

Case report: Xanthogranulomatous pyelonephritis masquerading as cystic renal cell carcinoma.

British journal of biomedical science·2020
Same author

MRA of the skin: mapping for advanced breast reconstructive surgery.

Clinical radiology·2018
Same author

Improving the quality of surgical care: The American College of Surgeons National Surgical Quality Improvement Program.

Revista de calidad asistencial : organo de la Sociedad Espanola de Calidad Asistencial·2017
Same author

The gene for the S7 ribosomal protein of Chlamydia trachomatis: characterization within the chlamydial sfr operon.

Molecular microbiology·2017
Same author

Caeco-peritoneal band as a potential cause of right iliac fossa pain in children.

Pediatric surgery international·2014
Same journal

Building Practical Artificial Intelligence Tools For The Plastic Surgeon: A Step-By-Step Guide To Cowork.

Plastic and reconstructive surgery·2026
Same journal

Interpretation Matters: Common Statistical Pitfalls in Retrospective Surgical Research.

Plastic and reconstructive surgery·2026
Same journal

"Inferior Repositioning of the High-Riding Nipple Using a Parenchymal-Based Flap".

Plastic and reconstructive surgery·2026
Same journal

A Four-Step Strategy for the Treatment of Facial Rhytids: A Focus on Upper Facial Wrinkles.

Plastic and reconstructive surgery·2026
Same journal

Evaluating Long-Term Retention of Fresh-Frozen Costal Cartilage Allograft in An Animal Model.

Plastic and reconstructive surgery·2026
Same journal

Manual extrusion of fat granules for primary thinning of a bulky flap.

Plastic and reconstructive surgery·2026
See all related articles

Microbial colonization, particularly Propionibacterium acnes and Staphylococcus epidermidis, is frequent in symptomatic silicone implants. This colonization was not significantly linked to implant rupture or patient symptoms.

Area of Science:

  • Microbiology
  • Biomaterials Science
  • Plastic Surgery

Background:

  • Microbial organisms are suspected in adverse effects for symptomatic silicone implant patients.
  • Previous studies identified various bacteria like Staphylococcus aureus and Clostridium perfringens in implant-related issues.
  • Infections in polyurethane-coated prostheses can increase patient morbidity.

Purpose of the Study:

  • To determine the frequency, type, and clinical relevance of microbial colonization on explanted silicone implants from symptomatic patients.
  • To investigate the impact of microbial colonization on implant integrity, including gel bleed and rupture.

Main Methods:

  • A prospective study analyzed 139 implants from 72 symptomatic patients (February 1993 - July 1994) at UCLA Medical Center.

Related Experiment Videos

  • Implants included various shell types (smooth, polyurethane, textured) and locations (subglandular, submuscular).
  • Cultures were performed on explanted implant surfaces; implant integrity (intact vs. ruptured) was assessed.

    • Main Results:

    • Of 139 implants, 31% were ruptured. 47% of implants were culture-positive.
    • Propionibacterium acnes (57.5%) and Staphylococcus epidermidis (41%) were the most common isolates; no fungal infections were found.
    • Culture positivity did not correlate significantly with systemic symptoms. 33% of culture-positive implants were ruptured.

    Conclusions:

    • Microbial colonization is common in symptomatic silicone implants, with P. acnes and S. epidermidis being predominant.
    • The study identified the frequency and types of microbial colonization in this patient group.
    • Further research may clarify the precise role of these microbes in implant-related symptoms and complications.