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Related Experiment Videos

Topical diclofenac relieves pain from corneal rust ring

R J Haynes1, S Walker, J N Kirkpatrick

  • 1Aberdeen Royal Infirmary, UK.

Eye (London, England)
|January 1, 1996
PubMed
Summary

Topical diclofenac significantly reduced pain in patients with corneal rust rings compared to placebo. This non-steroidal anti-inflammatory drug improved pain relief without affecting healing or inflammation rates.

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Area of Science:

  • Ophthalmology
  • Pharmacology

Background:

  • Corneal rust rings are common eye injuries.
  • Effective pain management is crucial for patient comfort.

Purpose of the Study:

  • To evaluate the efficacy of topical diclofenac for pain relief in corneal rust ring treatment.
  • To compare diclofenac's effect on pain, healing, and inflammation against a placebo.

Main Methods:

  • Prospective, double-masked, placebo-controlled trial.
  • 40 patients with corneal rust rings were enrolled.
  • Pain scores were assessed using visual analogue and Likert scales at 48 hours.

Main Results:

  • Diclofenac group showed significantly reduced pain scores (p=0.008 and p=0.042) compared to placebo.
  • No significant differences in epithelial healing rates between groups.
  • No significant differences in the degree of ocular inflammation between groups.

Conclusions:

  • Topical diclofenac provides effective analgesia for corneal rust rings.
  • Diclofenac improves pain management without compromising ocular healing or inflammation control.

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