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Acromegaly presenting with diabetic ketoacidosis
1Department of Endocrinology and Metabolic Medicine, University College London Hospitals NHS Trust, UK.
Postgraduate Medical Journal
|November 1, 1996
Abstract:
Diabetes in acromegaly is usually non-insulin dependent and is secondary to insulin resistance caused by growth hormone excess. Diabetic ketoacidosis is a result of relative insulin deficiency and is a rare feature of acromegaly. We describe a case of acromegaly presenting with diabetic ketoacidosis. We demonstrate that growth hormone excess can cause diabetic ketoacidosis in the presence of relative, but not absolute insulin deficiency.